By Edited by: Daniel L. Purich, Daniel L. Purich
This booklet is a component A in a subseries entitled "Amino Acid Metabolism". themes partially A might be of instant curiosity to people who are largely focused on amino acid assimilation and metabolism. Investigators attracted to enzyme mechanism and legislation also will locate this quantity specifically worthy.
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Extra resources for Amino Acid Metabolism, Part A, Volume 72, Advances in Enzymology and Related Areas of Molecular Biology
179, 1405-1411 (1949). Stadtman, E. , and Ginsburg, A . , IX, 755-807 (1974). Stadtman, E. R. , 182: 793-809 (1990). , Freeman, New York, 1988, p. 590. Todhunter, J. A. and Punch, D. , J. Biol. , 250, 3505-3509 (1975). Valentine, R. , Shapiro, B. , and Stadtman, E. , Biochemistry, 7, 2143-2152 (1%8). , and Voet, J. G. , Wiley, New York, 1995 p. 764. Wedler, F. , and Boyer, P. , J. Biol. , 247, 984-992 (1972). Wedler, F. C. Meth. , 249, 443-479 (1995). Weiss, V . , Proc. Natl. Acad. Sci. USA, 85, 8919-8923 (1988).
1962) reasoned that these conditions would favor the conversion of [ ‘‘C]glutamyl-P into radiolabeled y-glutamyl-hydroxamate, and only a minor amount of labeled product would result from the steady-state turnover of reactants into products after combining the pulse and chase solutions. This would be the case because any unbound [ 14C]glutamate would be diluted by the much larger pool of unlabeled glutamate, thereby assuring that the fraction of the diluted tracer y-glutamyl-hydroxamate would be minimal, even after multiple catalytic rounds.
Regulation of Glutamine Synthesis Integration of Glutamine Metabolism at the Acinar Level: Functional Relevance A. Glutamine Synthase as Perivenous Ammonia Scavenger B. Glutaminase: A pH and Hormone-Controlled Ammonia Amplifying System C. Intercellular Glutamine Cycling D. Role in Acid-Base Homeostasis ~~ Advances in Enzymology and Related Areas of Molecular Biology, Volume 72: Amino Acid Metabolism, Part A , Edited by Daniel L. Purich ISBN 0-471-24643-3 0 1998 John Wiley & Sons, Inc. 43 44 DIETER HAUSSINGER VIII.
Amino Acid Metabolism, Part A, Volume 72, Advances in Enzymology and Related Areas of Molecular Biology by Edited by: Daniel L. Purich, Daniel L. Purich